Description

The Park Lab at Boston Children’s Hospital, Harvard Medical School is seeking highly motivated applicants for a position of Postdoctoral Fellow. The NIH-supported position is to characterize how fundamental mechanisms of extracellular matrix (ECM) components regulate development and disease. For example, we found that proteoglycans coordinate basement membrane assembly and attenuate immune responses to limit inflammatory tissue injury, but that certain pathogens exploit these activities of proteoglycans to promote their pathogenesis. We have a strong interest in the cell biology of matrix remodeling, cell-matrix and matrix-pathogen interactions, matrix regulation of innate and adaptive immune responses, and tissue injury and repair. The work will be multidisciplinary and take advantage of genetically modified mice, engineered cell lines, high throughput technologies and diagnostics, patient samples, and a wide range of state-of-the-art techniques.

Requirements

Requirements include strong publications in one or several of the following fields: cell biology, microbiology, cell-matrix interactions, host-pathogen interactions, and pathogenesis of lung, liver, or ocular surface disease. A Ph.D. or M.D. degree and experience with basic molecular, biochemical, and cell biological techniques are required. Experience working with mice and ECM components is desirable. Fluent spoken and written English, and creative independent thinking are essential. We are most interested in candidates who received their doctoral degrees within the last 4 years. Qualified candidates should apply by sending a single PDF that includes a cover letter describing your background and specific research interests, current CV, and three reference contacts.